The present study aimed to gain more insight in the social behavioral phenotype, and related autistic symptomatology, of children with an extra X chromosome in comparison to children with ASD. Participants included 60 children with an extra X chromosome (34 boys with Klinefelter syndrome and 26 girls with Trisomy X), 58 children with ASD and 106 controls, aged 9 to 18 years. We used the Autism Diagnostic Interview, Social Responsiveness Scale, Social Anxiety Scale and Social Skills Rating System. In the extra X group, levels of social dysfunction and autism symptoms were increased, being in between controls and ASD. In contrast to the ASD group, the extra X group showed increased social anxiety. The effects were similar for boys and girls with an extra X chromosome. © Springer Science+Business Media 2013.
CITATION STYLE
Van Rijn, S., Stockmann, L., Borghgraef, M., Bruining, H., Van Ravenswaaij-Arts, C., Govaerts, L., … Swaab, H. (2014). The social behavioral phenotype in boys and girls with an extra X chromosome (Klinefelter syndrome and Trisomy X): A comparison with autism spectrum disorder. Journal of Autism and Developmental Disorders, 44(2), 310–320. https://doi.org/10.1007/s10803-013-1860-5
Mendeley helps you to discover research relevant for your work.