Sulfur bridged multidentate ligands based on (bi)pyridyl-(bi)-1,3,4- thiadiazolyl conjugates

Abstract

The synthesis of a series of mixed (bi)pyridyl/(bi)1,3,4-thiadiazolyl ligands, derived from the condensation of 2-mercapto-5-methylthio-1,3,4- thiadiazole or 5-mercapto-5′-methylthio-2,2′-bi-1,3,4-thiadiazole with 2,6-bis(chloromethyl)pyridine or 6,6′-bis(chloromethyl)-2,2′- bipyridine (compounds L1-L4), and of 2,5-dimercapto-1,3,4- thiadiazole or 5,5′-dimercapto-2,2′-di-1,3,4-thiadiazole with picolyl chloride hydrochloride or 6-chloromethyl-6′-methyl-2,2′- bipyridine (compounds L5-L8) in the presence of triethylamine is described. All new compounds have been characterized by FAB (+) spectrometry and NMR spectroscopy. 13C-NMR spectra are crucial to firmly establish the thiol structure of the title ligands.