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Examination of acute and chronic toxicity

Springer Berlin Heidelberg, (2014), 81-88
DOI: 10.1007/978-3-642-35374-1_31
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Abstract

Determination of the toxicological profile is necessarily related to the toxicity of a substance considering risk potential/risk estimation for human. Essential relevance includes the dose level as well as the application period. Studies considering acute, subacute, subchronic, and chronic intake are the basic which can be enlarged by specified studies. In general the results of those studies are relevant to set characteristic (LD 50/LC50 values, MOS, AOEL, ADI).

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Heimann, K. G., & Doughty, K. (2014). Examination of acute and chronic toxicity. In Regulatory Toxicology (pp. 81–88). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-642-35374-1_31

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