Regulatory T (Treg) cells are thought to be susceptible to conversion into effector T cells. In this issue of Immunity, Miyao et al. (2012) provide evidence that the apparent plasticity of murine Foxp3 + Treg cells is largely restricted to a defined subset of poorly committed Foxp3 + cells. © 2012 Elsevier Inc.
Hamann, A. (2012, February 24). Regulatory T Cells Stay on Course. Immunity. https://doi.org/10.1016/j.immuni.2012.02.004