Software for Full-Color 3D Reconstruction of the Biological Tissues Internal Structure

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Abstract

A software for processing sets of full-color images of biological tissue histological sections is developed. We used histological sections obtained by the method of high-precision layer-by-layer grinding of frozen biological tissues. The software allows restoring the image of the tissue for an arbitrary cross-section of the tissue sample. Thus, our method is designed to create a full-color 3D reconstruction of the biological tissue structure. The resolution of 3D reconstruction is determined by the quality of the initial histological sections. The newly developed technology available to us provides a resolution of up to 5–10 μm in three dimensions.

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Khoperskov, A. V., Kovalev, M. E., Astakhov, A. S., Novochadov, V. V., Terpilovskiy, A. A., Tiras, K. P., & Malanin, D. A. (2017). Software for Full-Color 3D Reconstruction of the Biological Tissues Internal Structure. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) (Vol. 10594 LNCS, pp. 1–10). Springer Verlag. https://doi.org/10.1007/978-3-319-69182-4_1

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