Non-Invasive Blood Glucose Measurement Using Quantum Cascade Lasers

  • Yoshioka K
  • Koyama T
  • Kino S
  • et al.
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Abstract

A non-invasive blood glucose measurement method using quantum cascade lasers (QCLs) oscillated in mid-infrared region is introduced. A mid-infrared spectroscopy system equipped with a combination of quantum cascade lasers (QCLs) as light sources and hollow-optical fibers as beam delivery media is developed. As the wavelengths of QCLs, the wavenumber of 1,152 cm⁻¹ that exhibited strong correlation with blood glucose in the optical absorption of human lips using FT-IR is firstly chosen. Then 1,186 cm⁻¹ where glucose shows no absorption is also chosen as a reference to remove effects of the baseline variation. By using the QCL-based system, it is shown that the differential absorption between these wavelengths exhibits high correlation with blood glucose level.

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Yoshioka, K., Koyama, T., Kino, S., & Matsuura, Y. (2018). Non-Invasive Blood Glucose Measurement Using Quantum Cascade Lasers. Nippon Laser Igakkaishi, 39(2), 105–110. https://doi.org/10.2530/jslsm.jslsm-39_0018

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