Throughout the 1960s and early 1970s, it was apparent to immunologists that the products of the MHC had a profound influence on immune responsiveness. So-called Ir genes that mapped within the MHC controlled the level of response, high vs low, to certain simple Ags. Another intriguing and well-
CITATION STYLE
Bevan, M. J. (2004). Altered Self, Altered World. The Journal of Immunology, 173(5), 2897–2898. https://doi.org/10.4049/jimmunol.173.5.2897
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