Biocompatible Electroconductive Matrices for Tissue Engineering: A Comparative Study

Abstract

Electroconductive polymer matrices intended for use in tissue engineering were prepared of various biocompatible polymers (polyimide, chitosan, copolyamide) modified with different conductive additives (graphene, carbon nanotubes, polypyrrole). Biocompatibility of matrices derived from composite materials was confirmed using human dermal fibroblast culture. Conducting properties of the matrices in the dry state and in physiological solution were investigated upon applying cyclic external potential. The influence of electron-conducting and ion-conducting components of the obtained composites on the current passing through the matrix and the shape of the current sweep is discussed.