Oral delivery of biopharmaceuticals

Abstract

For the past decade, oral drug delivery improved considerably in terms of drug innovations, new line extensions with better pharmacokinetic profiles, and thus, greater efficacy and patient compliance. In terms of R&D, the application of recent technologies and techniques, such as nanosizing or supercritical solutions, promoted this evolution as well as the recovery and readaptation of old fashion methods and well-known excipients, such as solid dispersions and conventional coating materials.