Role of cerebral blood volume in acute mountain sickness

Abstract

This review focuses on the role of cerebral blood volume in the intracranial hemodynamics that may influence the pathophysiology of acute mountain sickness (AMS). Cerebral blood flow is elevated in acute hypoxia exposure in humans, but the response in this setting of cerebral blood volume is unknown. After discussing the background, attention is given to noninvasive measurement of cerebral blood volume, and recent preliminary data on cerebral blood volume in AMS.