Adhesion of Staphylococcus Aureus on Various Biomaterial Surfaces

Abstract

At present, it is believed that 60 to 80% of the infections that humans encounter after implantation are related to the formation of biofilms. Biofilm-forming bacteria are particularly resistant to antibiotics and human immune mechanisms. This process is multistage, conditioned by the properties of the microorganisms that make it up, and by the structure and properties of the colonized materials. Therefore, it was proposed to apply the ZnO antibacterial layer on the substrate made of Ti6Al7Nb alloy by the ALD method. To evaluate the proposed surface modification, studies of electrochemical properties were carried out. In addition, biological studies were performed with the reference bacteria Staphylococcus aureus (ATCC 25923). The results show that the number of bacterial colonies adhered to the tested surfaces depends on the variant of used surface modification.