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Differences in Conformation and Conformational Dynamics Between Cisplatin and Oxaliplatin DNA Adducts

  • Chaney S
  • Ramachandran S
  • Sharma S
  • et al.
Humana Press, (2009), 157-169
DOI: 10.1007/978-1-60327-459-3_20
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Abstract

Abstract Some DNA damage-recognition proteins, transcription factors, mismatch repair proteins and DNA polymerases discriminate between cisplatin (CP)- and oxaliplatin (OX)-GG DNA adducts , and this is thought to help explain differences in efficacy, toxicity and ...

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Chaney, S. G., Ramachandran, S., Sharma, S., Dokholyan, N. V., Temple, B., Bhattacharyya, D., … Campbell, S. (2009). Differences in Conformation and Conformational Dynamics Between Cisplatin and Oxaliplatin DNA Adducts. In Platinum and Other Heavy Metal Compounds in Cancer Chemotherapy (pp. 157–169). Humana Press. https://doi.org/10.1007/978-1-60327-459-3_20

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