Phytochemical and acute toxicity studies of ethanol extract from pedada (Sonneratia caseolaris) fruit flour (PFF)

Abstract

Studies on the phytochemical and acute toxicity of pedada fruit flour (PFF) were carried out. In acute toxicity test, oral administration of the extract to Swiss albino mice at four levels dose, i.e. 0, 10.50; 15.75 and 21.00 g/kg body weight. Phytochemical analysis of the ethanol extract of PFF showed the presence of saponins, sapogenins, terpenoids, flavonoids, tannins, polyphenols. Phytochemicals such as alkaloids were not detected. The results of acute toxicity (LD50) showed that the ethanol extract of PFF in mice was found more than 21.00 g/kg body weight. It could be concluded that the PFF belongs to relatively less dangerous category 'non-toxic' and 'safe' for food products.