Bidirectional traffic on microtubules

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Abstract

Intracellular transport involves the processive displacement of molecular motors on microtubules. These motors are specialized to walk in one or the other direction on the microtubule. It is not known yet how this bi-directional traffic is organized in order to be efficient. Here we use some modeling based on cellular automata models to point out the problems caused by bidirectional transport, we discuss the role of confinement around the microtubule, and we illustrate how the dynamics of the microtubules could help preventing jam formation. © 2010 Springer-Verlag.

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Ebbinghaus, M., Appert-Rolland, C., & Santen, L. (2010). Bidirectional traffic on microtubules. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) (Vol. 6350 LNCS, pp. 542–551). https://doi.org/10.1007/978-3-642-15979-4_58

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