Molecular cloning of monkey histamine H4 receptor

Abstract

Histamine H4 receptor is considered as a novel therapeutic target for allergic diseases. To enhance the knowledge about species difference, which is essential for drug discovery research, monkey H4 receptor was identified. Monkey H4 receptor was characterized to have comparable similarity with its human counterpart. Discovery of monkey H 4 receptor will contribute to a better interpretation of effective drug discovery. ©2005 The Japanese Pharmacological Society.