Abstract
We estimated the effectiveness of booster doses of monovalent and bivalent mRNA COVID-19 vaccines against Omicron-associated severe outcomes among adults aged ≥50 years in Ontario, Canada. Monovalent and bivalent mRNA COVID-19 booster doses provided similar strong initial protection against severe outcomes. Uncertainty remains around waning of protection from these vaccines.
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Grewal, R., Buchan, S. A., Nguyen, L., Nasreen, S., Austin, P. C., Brown, K. A., … Kwong, J. C. (2024). Effectiveness of mRNA COVID-19 Monovalent and Bivalent Vaccine Booster Doses Against Omicron Severe Outcomes Among Adults Aged ≥50 Years in Ontario, Canada: A Canadian Immunization Research Network Study. Journal of Infectious Diseases, 229(2), 394–397. https://doi.org/10.1093/infdis/jiad419
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