Wound Healing Activity of Extracts of Malva sylvestris and Stachys lavandulifolia

  • Pirbalouti A
  • Koohpyeh A
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Abstract

The flowers of Stachys lavandulifolia Vahl (Lamiaceae) and Malva sylvestris Linn (Malvaceae) are traditionally used to treat various skin disorders, antimicrobial and anti-inflammatory. The chloroform extract of M. sylvestris flowers and aqueous extract of S. lavandulifolia flowers were used to evaluate the wound healing activity at 200 mg/kg/day dose . Wounds were induced in Wistar rats divided into four groups as following; Group-I was treated with cold cream . Groups-II and -III were treated with cold cream containing of extracts, Group-IV received the standard drug ( Nitrofurazone ). The efficacy of treatment was evaluated based on wound area and histopathological characteristics. The extract-treated animals by M. sylvestris showed significant reduction in the wound area when compared with other groups. Also, histopathological studies of the tissue obtained on days 6 th , 9 th and 16 th from the extract - treated by M. sylvestris showed increased well organized bands of collagen, more fibroblasts and few inflammatory cells.

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Pirbalouti, A. G., & Koohpyeh, A. (2010). Wound Healing Activity of Extracts of Malva sylvestris and Stachys lavandulifolia. International Journal of Biology, 3(1). https://doi.org/10.5539/ijb.v3n1p174

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