The ability of a tissue to respond to stress or injury requires the involvement and functions of stem cells resident in tissue-specific microenvironmental niches. Aging has been shown to result in a decrease in stem cell number as well as loss of ability to maintain tissue homeostasis and regenerate lost tissue function. Therefore, it is of critical importance to identify stem/progenitor cell populations in different tissues, determine how these cells function in tissue homeostasis, and ascertain their potential utility in tissue engineering.
CITATION STYLE
Sakai, D., & Mochida, J. (2014). Use of stem cells for regeneration of the intervertebral disc. In The Intervertebral Disc: Molecular and Structural Studies of the Disc in Health and Disease (pp. 373–383). Springer-Verlag Wien. https://doi.org/10.1007/978-3-7091-1535-0_23
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