Search for cellular phosphorylation products of D-allose

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Abstract

The all-cis hexose D-allose, fed to hamster fibroblast cultures over 14-20 hr, brings about a striking down-regulation of hexose transport. This down-regulation by allose is inhibited by 2,4-dinitrophenol. By using D-[14C]allose and thin-layer chromatography, two types of products accumulated that have been identified as allose and allose phosphate. We suspect that allose phosphate might be the down-regulator.

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Ullrey, D. B., & Kalckar, H. M. (1991). Search for cellular phosphorylation products of D-allose. Proceedings of the National Academy of Sciences of the United States of America, 88(4), 1504–1505. https://doi.org/10.1073/pnas.88.4.1504

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