Deciphering Metabolic Heterogeneity by Single-Cell Analysis

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Abstract

Single-cell analysis provides insights into cellular heterogeneity and dynamics of individual cells. This Feature highlights recent developments in key analytical techniques suited for single-cell metabolic analysis with a special focus on mass spectrometry-based analytical platforms and RNA-seq as well as imaging techniques that reveal stochasticity in metabolism.

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Evers, T. M. J., Hochane, M., Tans, S. J., Heeren, R. M. A., Semrau, S., Nemes, P., & Mashaghi, A. (2019). Deciphering Metabolic Heterogeneity by Single-Cell Analysis. Analytical Chemistry, 91(21), 13314–13323. https://doi.org/10.1021/acs.analchem.9b02410

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