Respiratory tract carrier rates of Moraxella (Branhamella) catarrhalis in adults and children and interpretation of the isolation of M. catarrhalis from sputum

Abstract

Nonselective media and previously described selective media were used to study the occurrence of Moraxella (Branhamella) catarrhalis in sputum samples of good and poor quality and in samples taken from different sites of the upper respiratory tracts of healthy subjects. It was found that in healthy adults the carrier rate was 5.4%, as opposed to 50.8% in children and 26.5% in people older than 60 years. M. catarrhalis was recovered significantly more often from sputum samples of good quality (5%) than from poor quality samples (0.5%), and when present, it was found mostly in the presence of high inocula. From these data gathered from healthy and diseased subjects, it is concluded that the presence of M. catarrhalis in the sputum of adults is rarely due to oronasopharyngeal contamination of the sputum. Similar findings reported by others are discussed, and the origins of the currently held concept that M. catarrhalis is a commensal organism of the human upper respiratory tract are traced.