Eucalyptol: A bio-based solvent for the synthesis of o,s,n-heterocycles. application to hiyama coupling, cyanation, and multicomponent reactions

Abstract

We report here the use of eucalyptol as a bio-based solvent for Hiyama coupling, cyanation, and multicomponent reactions on O,S,N-heterocycles. These heterocycles were chosen as targets or as starting materials given their biological potential; they play an important role in therapeutically active compounds. Once again, eucalyptol proved to be a credible and sustainable alter-native to common solvents.