A clean procedure for synthesis of benzo[c]acridine derivatives: Reaction of N-arylidenenaphthalen-1-amine with 5,5-dimethyl-1,3-cyclohexadione in aqueous medium

Abstract

A short and simple synthesis of 10,10-dimethyl-7-aryl-7,9,10,11-tetrahydro- 9H- benzo[c]acridin-8-one derivatives was accomplished in high yields via the reaction of N-arylidenenaphthalen-1-amine with 5,5-dimethyl-1,3-cyclohexadione in aqueous medium catalyzed by TEBAC. The structures were established from spectroscopic data and melting points. ©ARKAT.