Cytological studies of recombination in rhesus males

23Citations
Citations of this article
22Readers
Mendeley users who have this article in their library.
Get full text

Abstract

An immunofluorescence approach was used to directly examine meiotic recombination events in 483 pachytene spermatocytes from 11 male rhesus monkeys. Specifically, we examined the nuclear localization patterns of the DNA mismatch repair protein MLH1, known from analyses of other mammalian species to be a useful marker of meiotic cross-overs. Our results indicated that rhesus pachytene spermatocytes contain approximately 40 cross-overs per cell, corresponding to about one cross-over per chromosome. The chromosomal distribution of these exchanges was consistent with data from human and mouse males but, surprisingly, the overall number of foci was lower, and the number of 'exchangeless' bivalents higher, than reported for either humans or mice. Copyright © 2009 S. Karger AG, Basel.

Cite

CITATION STYLE

APA

Hassold, T., Hansen, T., Hunt, P., & Vandevoort, C. (2009). Cytological studies of recombination in rhesus males. Cytogenetic and Genome Research, 124(2), 132–138. https://doi.org/10.1159/000207519

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free