Retransplanting a previously transplanted kidney: A safe strategy in times of organ shortage?

Citations of this article
Mendeley users who have this article in their library.

This article is free to access.


Background: The shortage of organs for transplantation remains a global problem. The retransplantation of a previously transplanted kidney might be a possibility to expand the pool of donors. We provide our experience with the successful reuse of transplanted kidneys in the Eurotransplant region. Methods: A query in the Eurotransplant database was performed between January 1, 1995 and December 31, 2015, to find kidney donors who themselves had previously received a kidney graft. Results: Nine out of a total of 68,554 allocated kidneys had previously been transplanted. Four of these kidneys were transplanted once again. The mean interval between the first transplant and retransplantation was 1689±1682 days (SD; range 55–5,333 days). At the time of the first transplantation the mean serum creatinine of the donors was 1.0 mg/dl (.6–1.3 mg/dl) and at the second transplantation 1.4 mg/dl (.8–1.5 mg/dl). The mean graft survival in the first recipient was 50 months (2–110 months) and in the second recipient 111 months (40–215 months). Conclusion: Transplantation of a previously transplanted kidney may successfully be performed with well-preserved graft function and long-term graft survival, even if the first transplantation was performed a long time ago. Such organs should be considered even for younger recipients in carefully selected cases.




Karakizlis, H., van Rosmalen, M., Boide, P., Askevold, I., Vogelaar, S., Lorf, T., … Weimer, R. (2022). Retransplanting a previously transplanted kidney: A safe strategy in times of organ shortage? Clinical Transplantation, 36(3).

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free