The initiation of an adaptive immune response requires the presentation of self-antigens or foreign Ags to Ag-specific T lymphocytes. Seminal studies by R.M. Zinkernagel and P.C. Doherty ([1][1]) in the 1970s revealed that T cells only respond to their cognate Ag when it is seen in the context of
CITATION STYLE
Van Kaer, L. (2018). How Superantigens Bind MHC. The Journal of Immunology, 201(7), 1817–1818. https://doi.org/10.4049/jimmunol.1801104
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