Metal-based therapy in traditional and modern medicine systems

Abstract

Traditional medicine system is an integral part of therapy due to high extent of reliability, efficiency and cost-effectiveness. Ayurveda is the oldest traditional medicine system in India having a long history of use of metals in the form of Bhasma for the cure of various diseases. In addition to different other factors, the human metabolism needs various gases, elements and metals for the proper functioning. These metals are required in the adequate quantity for a specific physiological function of the body in order to ensure healthy and long life. Any imbalance in the levels of these metals results into alterations in the normal biochemical, physiological and behavioural functions leading to the onset of several diseases. The metals such as cobalt, copper, iron, selenium, zinc, etc. are the essential part of some enzymes and proteins called metalloenzymes and metalloproteins, and actively involved in the body metabolisms. These metals like selenium, copper and gold have also been successfully used in cancer therapy. There is a need of conducting extensive research in this area to establish appropriate formulation and application of different metals and metal-based nanomaterials to get the desired results with least side effects.