Molecular analysis of the sequences surrounding blaOXA-45 reveals acquisition of this gene by Pseudomonas aeruginosa via a novel ISCR element, ISCR5

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Abstract

The WaOXA-45 gene of Pseudomonas aeruginosa 07-406 is driven by a promoter found within a truncated ISPme1 insertion sequence. The gene is located between nonidentical repeats of a new ISCR element, 1SCR5, which is likely responsible for its acquisition. Sequence analysis indicates that ISCR5 is a chimera of 1SCR3 and ISCR16. Copyright © 2009, American Society for Microbiology. All Rights Reserved.

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Li, H., Walsh, T. R., & Toleman, M. A. (2009). Molecular analysis of the sequences surrounding blaOXA-45 reveals acquisition of this gene by Pseudomonas aeruginosa via a novel ISCR element, ISCR5. Antimicrobial Agents and Chemotherapy, 53(3), 1248–1251. https://doi.org/10.1128/AAC.00480-08

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