21-(4-Methyl-phenyl-sulfon-yl)-4,7,13,16-tetra-oxa-1,10, 21-triaza-bicyclo-[8.8.5]tricosane-19,23-dione: An N-tosyl-ated macrobicyclic dilactam

Abstract

The macrobicyclic title compound, C23H35N 3O8S, contains two tertiary amide bridgehead N atoms and a toluene-sulfonamide N atom in the center of the five-atom bridging strand. The mol-ecule has a central cavity that is defined by the 18-membered ring identified by the N2O4 donor atom set and two 15-membered rings with N3O2 donor atom sets. The toluene-sulfonamide N atom adopts an exo orientation with respect to the central cavity, and the tosyl group is oriented on one side of the aza-bridging strand that connects the bridgehead N atoms.