Spine surgery and fat embolism syndrome. Defining the boundaries of medical accountability by hospital autopsy

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Abstract

Background: Fat Embolism Syndrome (FES) is a clinical condition characterized by neurological, respiratory, hematological and cutaneous manifestations. Fatal FES has been described as a rare complication during or after spinal elective surgery. The investigation of the cause of death in fatalities related with spine surgery should be mandatory to exclude or confirm fat embolism; a detailed methodological approach to the body in these cases suggests to provide a cautious dissection of surgical site and collection of samples to detect embolized fat globules in vessels. Methods: Two fatal cases of fat embolism syndrome after posterior spinal fusion are presented. Conclusions: A complete post mortem examination by means of histochemical and immunohistochemical analysis explained the cause of death and prevented medical malpractice litigation.

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Radaelli, D., Zanon, M., Concato, M., Fattorini, P., Alfieri, L., Marino, R., … D’Errico, S. (2021). Spine surgery and fat embolism syndrome. Defining the boundaries of medical accountability by hospital autopsy. Frontiers in Bioscience - Landmark, 26(12), 1760–1768. https://doi.org/10.52586/5067

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