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Emerging links between m6A and misregulated mRNA methylation in cancer

Genome Medicine
DOI: 10.1186/s13073-016-0395-8
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Abstract

N6-methyladenosine (m6A) in mRNA has emerged as a crucial epitranscriptomic modification that controls cellular differentiation and pluripotency. Recent studies are pointing to a role for the RNA methylation program in cancer self-renewal and cell fate, making this a new and promising therapeutic avenue for investigation.

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Jaffrey, S. R., & Kharas, M. G. (2017, January 12). Emerging links between m6A and misregulated mRNA methylation in cancer. Genome Medicine. BioMed Central Ltd. https://doi.org/10.1186/s13073-016-0395-8

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