Correlation between phytoestrogens intake with telomere length in minangkabau premenopausal women

Abstract

Objective: This study aimed to investigate the correlation between phytoestrogens intake with telomere length in premenopausal Minangkabau ethnicity women. Methods: This cross-sectional study was conducted in Padang city, to 113 premenopausal Minangkabau ethnic 40–54 years old. Food intake data were obtained by an interview by trained enumerators using semi-quantitative food frequency questionnaire. Telomere examination was done from 3 ml of venous blood. Telomere length examination by modification of O’Callaghan and Fenech method. Estradiol level was measured by the ELISA technique. Results: This research indicated an average telomere length was 554.79±426.81 bp, estradiol level was 149.47±52.26 pg/ml, and phytoestrogens intake was 37.95±32.25 mg/day. There were the differences between phytoestrogens intake and telomere length based on estradiol levels. Then, there was no significant correlation between phytoestrogens intake and telomere length. Conclusion: There is no significant positive correlation between phytoestrogens intake and telomere length of premenopausal women in the Minangkabau ethnic.