Anti-inflammatory and anti-nociceptive effects of ethanolic extract of Setaria megaphylla leaves in rodents

Abstract

The ethanolic leaf extract of Setaria megaphylla (100-300 mg/kg) was investigated for pharmacological properties against egg white albumin-induced inflammation, Chemical as well as thermal-induced pain. The extract demonstrated a dose-dependent anti-inflammatory and antinociceptive activities. These activities were comparable to that of ASA (100mg/kg). The leaf extract possess anti inflammatory and analgesic properties, which can be exploited in health care (Afr. J. Biomed. Res. 9: 229-233)