Tumors can evade conventional T cell recognition by rendering the HLA class I antigen presentation system defective. In a recent study, de Vries et al. reveal γδ T cells as key contributors to the efficacy of immune checkpoint blockade (ICB) against HLA-I-silenced cancers, highlighting a novel layer of surveillance against immune escape by tumors.
CITATION STYLE
Koay, H. F., & Lynch, L. (2023, March 1). γδ T cells unveil invisible tumors. Trends in Immunology. Elsevier Ltd. https://doi.org/10.1016/j.it.2023.01.011
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