Patient with neuromyelitis optica spectrum disorder combined with Sjögren's syndrome relapse free following tacrolimus treatment

7Citations
Citations of this article
30Readers
Mendeley users who have this article in their library.

Abstract

Tacrolimus, a novel immunosuppressant agent, has been widely used in organ transplantation and autoimmune diseases. We herein present a case of neuromyelitis optica spectrum disorder (NMOSD) combined with Sjögren's syndrome (SS) successfully treated with tacrolimus. This patient repeatedly presented with recurrent longitudinally extensive transverse myelitis. Her NMO-IgG and anti-SSA and anti-SSB antibodies were seropositive. Considering the frequency of relapses and severe disability, tacrolimus was initiated after failure of intravenous cyclophosphamide. Her status was steady for over 36 months after tacrolimus treatment. This report indicates that tacrolimus may be a potentially effective immunosuppressant for NMOSD with systemic autoimmune diseases.

Cite

CITATION STYLE

APA

Zheng, X., Zhang, X., Liu, X., Mu, W., Yang, W., Liu, Y., … Li, H. (2014). Patient with neuromyelitis optica spectrum disorder combined with Sjögren’s syndrome relapse free following tacrolimus treatment. Internal Medicine, 53(20), 2377–2380. https://doi.org/10.2169/internalmedicine.53.0814

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free