LC-MS/MS- and GC-MS-based targeted metabolomics is typically conducted by analyzing and quantifying a cascade of metabolites with methods specifically developed for the metabolite class. Here we describe an approach for the development of multi-residue analytical profiles, calibration standards, and internal standard solutions in support of a fast, simple, and low-cost plasma sample preparation that captures and quantitates a range of metabolite cascades.
CITATION STYLE
Pedersen, T. L., & Newman, J. W. (2018). Establishing and performing targeted multi-residue analysis for lipid mediators and fatty acids in small clinical plasma samples. In Methods in Molecular Biology (Vol. 1730, pp. 175–212). Humana Press Inc. https://doi.org/10.1007/978-1-4939-7592-1_13
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