DNA replication profiling using deep sequencing

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Abstract

Profiling of DNA replication during progression through S phase allows a quantitative snap-shot of replication origin usage and DNA replication fork progression. We present a method for using deep sequencing data to profile DNA replication in S. cerevisiae.

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Saayman, X., Ramos-Pérez, C., & Brown, G. W. (2018). DNA replication profiling using deep sequencing. In Methods in Molecular Biology (Vol. 1672, pp. 195–207). Humana Press Inc. https://doi.org/10.1007/978-1-4939-7306-4_15

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