The intentional infection of human beings with pathogens with the aim of achieving benefits (chiefly, the prevention of more severe disease) has occurred for centuries; the (semi-)systematic testing and recording of such methods dates to the 18th Century in England.
CITATION STYLE
Jamrozik, E., & Selgelid, M. J. (2021). History of Human Challenge Studies. In SpringerBriefs in Ethics (pp. 9–23). Springer Nature. https://doi.org/10.1007/978-3-030-41480-1_2
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