Determination of the stability constants of benzene and alkylbenzenes with α-cyclodextrin by static head-space gas chromatography

Abstract

The stability constants for the inclusion of benzene and alkylbenzenes with α-cyclodextrin (α-CyD) in aqueous solution have been determined using static head-space gas chromatography (SHSGC). The 1:1 and 2:1 (host:guest) stability constants obtained by this method were in reasonable agreement with the corresponding values in the literature. Therefore, it was concluded that the SHSGC method is useful for determining the stability constant of the volatile compound/CyD complex.