Background: Microfluidic platforms have demonstrated the ability to isolate rare circulating tumor cells from a wide variety of cancers. Our group has recently shown the ability to isolate circulating tumor cells (CTCs) from hepatocellular carcinoma (HCC) patients using a hematopoietic cell depletion microfluidic platform. However, the relationship of CTC generation and HCC progression is still not well understood. Tumor size is often used as a clinical prognostic factor, but there has been an inconsistent relationship of tumor size and metastatic recurrence. Characterizing the relationship of primary tumor size and CTCs would provide a better understanding of HCC tumor size and metastatic potential.
CITATION STYLE
Oklu, R., Sheth, R., Albadawi, H., Bhan, I., Fatih Sarioglu, A., Choz, M., … Ting, D. T. (2018). Relationship between hepatocellular carcinoma circulating tumor cells and tumor volume. Cancer Convergence, 2(1). https://doi.org/10.1186/s41236-018-0009-z
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