This case discusses the pharmacokinetic interaction of atorvastatin and phenytoin. Atorvastatin is a cytochrome P450 3A4 substrate and phenytoin is a paninducer of multiple cytochrome P450 enzymes including 3A4.
CITATION STYLE
Mitchell, B. (2015). The statin trilogy (III): Welcome to the united “Statins” of America: Fatal Forty DDI: Atorvastatin, phenytoin, CYP3A4. In A Case Approach to Perioperative Drug-Drug Interactions (pp. 627–629). Springer New York. https://doi.org/10.1007/978-1-4614-7495-1_139
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