Chemical structure of the core region of Campylobacter jejuni serotype O:2 lipopolysaccharide

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Abstract

The complete structure for the core region of Campylobacter jejuni serotype O:2 lipopolysaccharide (LPS) was assigned through studies on derivatives of the liberated oligosaccharide (OS 2) and the intact LPS. Structure determinations were performed using 1H‐NMR spectroscopy, methylation studies supported by fast‐atom‐bombardment mass spectrometry and linkage analysis by gas chromatography/mass spectrometry, Smith degradation, and oxidation with chromium trioxide. It was concluded that complete oligosaccharide chains had the following structure: (Formula Presented.) Copyright © 1993, Wiley Blackwell. All rights reserved

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ASPINALL, G. O., McDONALD, A. G., RAJU, T. S., PANG, H., KURJANCZYK, L. A., PENNER, J. L., & MORAN, A. P. (1993). Chemical structure of the core region of Campylobacter jejuni serotype O:2 lipopolysaccharide. European Journal of Biochemistry, 213(3), 1029–1037. https://doi.org/10.1111/j.1432-1033.1993.tb17850.x

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