Biomarker-driven adaptive design

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Abstract

We review some principles and implementations of Bayesian model-based adaptive enrichment and population finding designs that exploit biomarker information to propose adaptive treatment allocation and recommend patient subpopulations that might most benefit from the treatments under consideration.

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Xu, Y., Ji, Y., & Müller, P. (2015). Biomarker-driven adaptive design. In Nonparametric Bayesian Inference in Biostatistics (pp. 311–326). Springer International Publishing. https://doi.org/10.1007/978-3-319-19518-6_15

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