Transmission blocking immunity as observed in a feeder system and serological reactivity to Pfs 48/45 and Pfs230 in field sera.

W. Roeffen; T. Lensen; B. Mulder; K. Teelen; R. Sauerwein; W. Eling; J. H. Meuwissen; P. Beckers

Journal ArticleOPEN ACCESS

Transmission blocking immunity as observed in a feeder system and serological reactivity to Pfs 48/45 and Pfs230 in field sera.

Roeffen W
Lensen T
Mulder B
et al.

Memórias do Instituto Oswaldo Cruz (1994) 89 Suppl 2 13-15

DOI: 10.1590/S0074-02761994000600004

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Abstract

Monoclonal antibodies (mAbs) and human sera from gametocyte carriers were applied in the bio-assay to test for their transmission-blocking capacity. Competition ELISA's have been developed for the detection of natural transmission blocking antibodies. Approximately 55% of the sera blocking in the bio-assay gave positive results in these competition ELISA's.

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Roeffen, W., Lensen, T., Mulder, B., Teelen, K., Sauerwein, R., Eling, W., … Beckers, P. (1994). Transmission blocking immunity as observed in a feeder system and serological reactivity to Pfs 48/45 and Pfs230 in field sera. Memórias Do Instituto Oswaldo Cruz, 89 Suppl 2, 13–15. https://doi.org/10.1590/S0074-02761994000600004

Transmission blocking immunity as observed in a feeder system and serological reactivity to Pfs 48/45 and Pfs230 in field sera.

Abstract

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