Transmitted light microscopy can readily visualize the morphology of living cells. Here, we introduce artificial-intelligence-powered transmitted light microscopy (AIM) for subcellular structure identification and labeling-free functional analysis of live cells. AIM provides accurate images of subcellular organelles; allows identification of cellular and functional characteristics (cell type, viability, and maturation stage); and facilitates live cell tracking and multimodality analysis of immune cells in their native form without labeling.
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CITATION STYLE
Kim, D., Min, Y., Oh, J. M., & Cho, Y. K. (2019). AI-powered transmitted light microscopy for functional analysis of live cells. Scientific Reports, 9(1). https://doi.org/10.1038/s41598-019-54961-x