Case report: Reversible posterior leukoencephalopathy in a venomous snake (Bothrops asper) bite victim

Abstract

An 18-year-old man developed posterior reversible leukoencephalopaty after being bitten by a venomous snake (Bothrops asper). It is possible that this previously unrecognized neurological complication of snake bite envenoming occurred as the result of endothelial dysfunction induced by the venom of the offending snake. This pathogenetic mechanism has also been implicated as the cause of cerebral infarctions in snake bite victims. Alternatively, the leukoencephalopathy might have been a complication of antivenom therapy. Copyright © 2012 by The American Society of Tropical Medicine and Hygiene.