Variability of intra-aneurysmal hemodynamics caused by stent-induced vessel deformation

Abstract

Clinical observation revealed deformations of the local vasculature due to implanted devices related to treatment of intracranial aneurysms. Pre- and post-interventional image data is reviewed and segmented. Based on Computational Fluid Dynamics (CFD) the effect of the vessel deformation on the intra-aneurysmal hemodynamics is investigated. The simulations incorporate the vessel trees with aneurysm excluding the device itself in order to consider the isolated effect of geometric modifications. As a result, the aneurysm inflow jet is redirected, changing the local flow quantities. Finally, a neck inflow rate reduction of 52.5 % is archived. Thus, a targeted vessel straightening as a novel tool for treatment planning appear to be an idea worth to discuss in the community.