Facial emotion processing was examined in patients with severe depression (n = 68) and a healthy control group (n = 50), using the Facial Expression Recognition Task. A negative interpretation bias was observed in the depression group: neutral faces were more likely to be interpreted as sad and less likely to be interpreted as happy, compared with controls. The depression group also displayed a specific deficit in the recognition of facial expressions of disgust, compared with controls. This may relate to impaired functioning of frontostriatal structures, particularly the basal ganglia.
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Douglas, K. M., & Porter, R. J. (2010). Recognition of disgusted facial expressions in severe depression. British Journal of Psychiatry, 197(2), 156–157. https://doi.org/10.1192/bjp.bp.110.078113