Abstract
The use of RNA interference (RNAi) to evoke gene silencing in mammalian cells has almost become routine laboratory practice. Through refinement of double-stranded RNA (dsRNA) triggers of RNAi and creation of genome-scale libraries, the first genome-wide loss of function screens have been carried out in mammals. This review discusses some of the key features of RNAi in mammalian systems. © 2008 Springer-Verlag.
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CITATION STYLE
APA
Paddison, P. J. (2008). RNA interference in mammalian cell systems. Current Topics in Microbiology and Immunology. https://doi.org/10.1007/978-3-540-75157-1_1
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