Analyses of programmed cell death in dendritic cells

Abstract

Dendritic cells (DCs) are professional antigen-presenting cells that can regulate both innate and adaptive immune responses. Programmed cell death of DCs plays an important role in maintaining the homeostasis of DCs and in the regulation of immune responses. Methods to measure the rate of spontaneous and T cell-mediated cell death of DCs are described here. These procedures can be adapted to study the induction of dendritic cell death in different settings of immune responses. © Springer Science+Business Media New York 2013.